Research article

DETERMINATION OF A NUMBER OF PHYSIOLOGICAL AND IMMUNOLOGICAL ASPECTS OF THE EFFECT OF CANDIDA ALBICANS ON FEMALE RATS AND THEIR TREATMENT WITH AQUEOUS EXTRACT OF DANDELION ROOT AND FLUCONAZOLE

Abdalrahim H. Eefan, Farah Rami Saleh

Online First: June 10, 2023


The current study aimed to know the physiological, immunological and biochemical effects of C. albicans fungi on the female reproductive system of rats and the therapeutic role of the aqueous extract of dandelion roots in the blood and the reproductive system throughout the duration of the experiment, and to compare these effects with the role of this aqueous extract of dandelion roots in synergy with tetracycline and flucanazole. The experiment started in May 20/04/2021 until 1/6/2021 for a period of (42) days. The number of (35) rats of (12-14) weeks old were distributed, and the animals were distributed into two groups, the first group being infected by (20) A rat was first treated with the hormone estradiol, where it was injected with 0.5 mg subcutaneously for 6 days every two days, and then a section of these animals was injected vaginally with C. albicans and also for 6 days, with an injection every two days, and then the experiment was conducted, as all the animals were distributed On 7 groups, each group has 5 rats.

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