UNVEILING NEGOMBATA MAGNIFICA: A PROMISING FRONTIER IN ANTICANCER RESEARCH

Over the last several years, marine organisms have shown to be a rich resource of novel bioactive compounds for use in the creation of new medicines. Therefore, many researchers have been trying to isolate new active compounds from marine organisms since the middle of the twentieth century. The rich variety of secondary metabolites found in marine sponges has made them a potential treasure trove. Many chemicals identified from sponges have anticancer potential. "The current research looked at whether or not Negombata magnifica has any antiproliferative properties.'' Multiple cellular and molecular mechanisms, including DNA protection, cell-cycle modulation, apoptosis, and anti-inflammatory activities, as well as the ability to chemosensitize cancer cells to conventional antiblastic chemotherapy, may account for the chemopreventive and potential anticancer activity of compounds from Negombata magnifica. The purpose of this article is to illustrate the interplay between the several systems responsible for Negombata magnifica's chemopreventive and therapeutic actions. Researchers have shown that NPs may serve as either a new therapeutic molecule or a useful framework for the production of novel bioactive compounds, both of which are crucial steps in the drug development process. The need of demonstrating practical mariculture technology of possible candidate marine sponges in India is also highlighted in the study, as this would allow for the pharmaceutical demands to be met without impacting the wild population.